Reply to Kaufman

Studies of lead exposure and the developing central nervous system: a reply to Kaufman.

Kaufman's critique of the lead-cognition hypothesis is a reiteration of well worn and weary claims raised many times in the past, primarily by spokespersons for the lead industry. They have been fully rebutted in the literature. The essence of these claims is that those studies showing an association between lead and IQ are flawed by uncontrolled confounding, multiple comparisons, and errors in...

McKusik Kaufman syndrome.

A 12-years-old male child presented with polydactyly and syndactyly of hands, hypospadias, AND undescended testes. He was a known case of Tetrology of Fallot. One important differential in our case was Bardet-Biedl syndrome, but it was ruled out due to lack of evidence of central obesity, mental retardation and retinitis pigmentosa. At this time, there is no molecular testing available to disti...

The Authors’ Reply

Joseph J. Kaufman: renaissance man.

Joseph J. Kaufmanwas born inNewHaven,Connecticut, on February 10, 1921 toKarl andTiny Kaufman. The family moved shortly thereafter to open a millinery shop in Worcester, Massachusetts. As a child of first-generation Jewish Romanians, his life in Blue Collar, Worcester, was challenging. Kaufman and his friends took turns “on patrol” whenwalking home from school to protect themselves from anti-Se...

Mckusick-Kaufman Syndrome: Diagnosis and Management

A female newborn, a product of consanguineous marriage born by caesarian section delivery with a birth weight of 3.75 kg, was admitted to our hospital with abdominal distension. Antenatal ultrasound showed congenital heart disease and a pelvic mass. On examination, she had lower abdominal mass emanating from the pelvis. There was polydactly and syndactly of the right hand and polydactly of the ...